Calculate Target AUC
The calculation of the Target AUC of Carboplatin is necessary to determine dosing and to identify potential toxicity. To adjust the Target AUC, click on the drug name to modify the dose information.
Change the Carboplatin Dose
Change the dose if necessary by manually typing in the Dose field.
The Dose can also be selected using the QUICK SIG PICK button.
The creatinine result is populated from the patient chart if the result was received by the lab interface. If the test was performed at an outside lab, type the result in the S. Creatinine field.
Adjust the Dose
Click ADJUST DOSE to make additional modifications to the dosing information.
Use the Dose Calculator
In the Dose Calculator/Formula Amount/Adjust window make changes to the:
Dose Amount and Unit information
Creatinine Clearance Calculation Method
Serum Creatinine value
Adjusted Amount
To round the calculated result, use the Adjusted Amount field. Click UPDATE ORDER to save the changes.
Handling Abnormally Low Creatinine Values
To order Carboplatin for a patient with a serum creatinine less than 0.7 mg/dl, the system will calculate the dose based on the patient's actual serum creatinine result and the NCCN recommendation.
Advance to Next Medication
After modifying the medication, click NEXT ORDER to advance to the next medication in the regimen or click OK to return to the list of medications in the regimen.
Target AUC in Regimen Order Screen
From the Regimen Ordering screen, you also have the option to click on the Carboplatin dose amount to bring up the Quick Sig list to modify the dose and Target AUC information.
Adjust the Calculated Dose in Regimen Order Screen
To update the calculated dose manually from the regimen order screen, click the Calculated Dose amount and enter the information in the Adjusted Amount field.
Click OK to update the Dose.
Review the Regimen Order
After adjusting the Carboplatin dose, click REVIEW / SAVE to go to the Order Review screen and complete the order.